Opis: Heparin-Induced Thrombocytopenia - Erwin Warkentin

Summarizes research in heparin-induced thrombocytopenia (HIT), an antibody-mediated prothrombotic drug reaction without parallel in clinical medicine. Views HIT as a clinicopathologic syndrome, and stresses the importance of in vivo thrombin generation in the pathogenesis of HIT. Describes HIT's variable frequency and clinical presentation among different populations treated with heparin. Specific subjects include immune vascular injury in HIT, laboratory testing, hemodialysis, and legal aspects. Warkentin teaches pathology and molecular medicine at McMaster University, Canada.History of heparin-induced thrombocytopenia; differential diagnosis of acute thrombocytopenia; clinical picture of heparin-induced thrombocytopenia; frequency of heparin-induced thrombocytopenia; nonimmune heparin/platelet interactions -implications for the pathogenesis of heparin-induced thrombocytopenia; heparin-dependent antigens in heparin-induced thrombocytopenia; molecular immunopathogenesis of heparin-induced thrombocytopenia; role of sulfated polysaccharides in the pathogenesis of heparin-induced thrombocytopenia; the platelet Fc receptor in heparin-induced thrombocytopenia; immune vascular injury in heparin-induced thrombocytopenia; laboratory testing for heparin-induced thrombocytopenia; pseudo-heparin-induced thrombocytopenia; treatment of heparin-induced thrombocytopenia -an overview; danaparoid for the treatment of heparin-induced thrombocytopenia; recombinant hirudin for the treatment of heparin-induced thrombocytopenia; haemodialysis in heparin-induced thrombocytopenia; management of cardiopulmonary bypass anticoagulation in patients with heparin-induced thrombocytopenia; legal aspects of heparin-induced thrombocytopenia; appendices -clinical rules for the use of anticoagulants, treatment recommendations, danaparoid dosing schedules, dosing schedules for r-hirudin treatment of patients with HIT.

Szczegóły: Heparin-Induced Thrombocytopenia - Erwin Warkentin

Tytuł: Heparin-Induced Thrombocytopenia
Autor: Erwin Warkentin
Producent: Marcel Dekker
ISBN: 9780824702717
Rok produkcji: 2000
Ilość stron: 416
Oprawa: Twarda

Recenzje: Heparin-Induced Thrombocytopenia - Erwin Warkentin