Opis: Immune Interferon - Ivan Ivanov, Roumen G. Tsanev, I Ivanov

Now for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Immune Interferon: Properties and Clinical Applications is essential reading for anyone working with interferons.Having developed their own brand of interferon-gamma, the authors have become well known for their research and significant contributions in the fields of molecular biology, biochemistry, and interferon-gamma. They bring together the extensive findings from years of research since the discovery of the drug. Focusing on the drug itself and not particular brands, the book presents data on the properties of interferon-gamma, experimental data on its effects in cell cultures in vitro and on animals in vivo, the role that IFN-gamma plays in different diseases, and the results of its clinical applications.As interest in this versatile drug continues to grow, new avenues for its clinical use will continue to arise. Within a single source, Immune Interferon: Properties and Clinical Applications provides you with thorough information on all facets of interferon-gamma, from biological properties, to pharmaceutical processing, to clinical application. "an excellent review of indications studied and under study and the outcomes of IFNg, as well as an exhaustive collection of references for these indications. A briefer overview of the preclinical and pharmacologic aspects of IFNg is provided." - James E. Talmidge, Ph.D., University of Nebraska Medical School in Doody's NotesFORWARD ABBREVIATIONS THE CYTOKINE FAMILY INTERFERON GAMMA(IFNg) Differences Between IFNg and IFN a/b Interferon-Producing Cells. Inducers and Inhibitors. Effect of Aging Structure and Physico-Chemical Properties of IFNg Interferon Gamma Receptors BIOLOGICAL ACTIVITIES OF INTERFERON GAMMA Antiviral Activity Antiproliferative Activity Immunostimulatory Activity Modulation of Gene Activity Antibacterial Activity Antitumor Activity MOLECULAR MECHANISMS OF IFNg ACTIVITIES. TRANSMEMBRANE SIGNAL TRANSDUCTION PRODUCTION OF INTERFERON GAMMA GAMMA-INTERFERON PREPARATIONS Interferon Gamma-1b Gammaferon Others INDICATIONS AND CONTRAINDICTIONS ROUTES OF ADMINISTRATION, PHARMACOKINETICS, DOSAGE SIDE EFFECTS INFECTIOUS DISEASES Viral Infections Herpes Simplex Type I and Type II Herpes Zoster Herpetic and Adenoviral Eye Infections Respiratory Viral Infections Human Papilloma Viruses (HPVs) HIV Infection Hepatitis Non-Viral Intracellular Pathogens Fungi Non-Viral Extracellular Pathogens NON-INFECTIOUS NON-MALIGNANT DISEASES Fibroproliferative Diseases Atherosclerosis Multiple Sclerosis (MS) Psoriasis Chronic Granulomatous Disease (CGD) Skin Ulcers in Autoimmune Vasculitis Rheumatoid Arthritis (RA) Osteopetrosis Allergic Disorders Lupus Erythematosus (SLE) Heavy Traumas, Burns and Surgical Operations MALIGNANT DISEASES Background for Using IFNg in Malignancies Basocellular Skin Cancer (Basalioma) Cancer of the Larynx Lung Cancer Colorectal Cancer Malignant Melanoma Renal Cell Carcinoma (RCC) Breast Cancer Cervical Cancer Gastric Cancer Prostate Cancer Ovarian Cancer Cancer of the Bladder Hepatocellular Carcinoma (HCC) Sarcomas Kaposi's Sarcoma Neuroblastoma Gliomas/Glyoblastomas Hematologic Malignancies Chronic Myelogenic Leukemia (CML) B and T Chronic Lymphatic Leukemias (B-CLL and T-CLL) Acute Leukemias Lymphomas Myelodisplastic Syndrome (MDS) Multiple Myeloma (MM) Conclusions on the Use of IFN-g In Malignant Diseases GENERAL CONCLUSIONS REFERENCES

Szczegóły: Immune Interferon - Ivan Ivanov, Roumen G. Tsanev, I Ivanov

Tytuł: Immune Interferon
Autor: Ivan Ivanov, Roumen G. Tsanev, I Ivanov
Producent: CRC Press Inc.
ISBN: 9780849311482
Rok produkcji: 2001
Ilość stron: 320
Oprawa: Twarda
Waga: 0.62 kg

Recenzje: Immune Interferon - Ivan Ivanov, Roumen G. Tsanev, I Ivanov