Opis: Advanced Electroporation Techniques in Biology and Medicine - Andrei G. Pakhomov, Damijan Miklavcic, Marko S. Markov

A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, "Advanced Electroporation Techniques in Biology and Medicine" summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and including contributions from pioneers in the field, the book focuses on biophysical mechanisms of electroporation and applications of this phenomenon in biomedical research and medicine. The field of electroporation is now mature enough to move from journal pages to book covers. The book leads readers from the basics and history of electroporation, through mechanisms of membrane permeabilization in lipid bilayers and living cells, to electrically-mediated gene delivery and cancer therapy in animals and humans. This book is an interdisciplinary compilation intended broadly for biomedical and physical scientists, engineers, and clinicians. It can also be used as a textbook for students in advanced courses in biomedical engineering, molecular and cell biology, as well as in biophysics and clinical medicine.Basics of Electroporation Physical Chemical Theory of Membrane Electroporation and Electrotransfer of Biogenic Agents, E. Neumann and S. Kakorin Bioelectric Effect of Intense Nanosecond Pulses, K.H. Schoenbach Induced Transmembrane Voltage-Theory, Modeling, and Experiments, T. Kotnik and G. Pucihar Electroporation: A Review of Basic Problems in Theory and Experiment, M.S. Markov Mechanisms of Electroporation in Lipid Systems Electrodeformation, Electroporation, and Electrofusion of Cell-Sized Lipid Vesicles, R. Dimova Fluorescent Methods in Evaluation of Nanopore Conductivity and Their Computational Validation, M. Kotulska, W. Dyrka, and P. Sadowski Electroporation of Lipid Membranes: Insights from Molecular Dynamics Simulations, M. Tarek and L. Delemotte Nanoscale Restructuring of Lipid Bilayers in Nanosecond Electric Fields, P.T. Vernier Mechanisms of Electroporation of Cells Nanopores: A Distinct Transmembrane Passageway in Electroporated Cells, A.G. Pakhomov and O.N. Pakhomova Model of Cell Membrane Electroporation and Transmembrane Molecular Transport, D. Miklavcic and L. Towhidi Kinetics of Pore Formation and Disappearance in the Cell during Electroporation, G. Saulis The Pulse Intensity-Duration Dependency for Cell Membrane Electroporation, D. Miklavcic, G. Pucihar, A.M. Lebar, J. Krmelj, and L. Towhidi Mechanisms of Electroporation in Tissues Drug-Free, Solid Tumor Ablation by Electroporating Pulses: Mechanisms That Couple to Necrotic and Apoptotic Cell Death Pathways, A.T. Esser, K.C. Smith, T.R. Gowrishankar, and J.C. Weaver Gene Electrotransfer: From Basic Processes to Preclinical Applications, J.-M. Escoffre, A. Paganin-Gioanni, E. Bellard, M. Golzio, M.-P. Rols, and J. Teissie Technical Considerations Modeling Electric Field Distribution In Vivo, N. Pavselj, A. Zupanic, and D. Miklavcic Concepts of Electroporation Pulse Generation and Overview of Electric Pulse Generators for Cell and Tissue Electroporation, M. Rebersek and D. Miklavcic Generation of Ultrashort Pulses, J.F. Kolb Nanosecond Pulsed Electric Field Delivery to Biological Samples: Difficulties and Potential Solutions, A. Silve, J. Villemejane, V. Joubert, A. Ivorra, and L.M. Mir Applications of Electroporation Translation of Electroporation-Mediated DNA Delivery to the Clinic, L.C. Heller and R. Heller Clinical Electrochemotherapy: The Italian Experience, C.R. Rossi and L.G. Campana Tumor Blood Flow-Modifying Effects of Electroporation and Electrochemotherapy-Experimental Evidence and Implications for the Therapy, T. Jarm, M. Cemazar, and G. Sersa lectrochemotherapy as Part of an Immunotherapy Strategy in the Treatment of Cancer, J. Gehl ombined Electrical Field and Ultrasound: A Nondrug-Based Method for Tumor Ablation, P.F. Forde, C. Twomey, G.C. O' Sullivan, and D. M. Soden Combined Modality Therapy: Electrochemotherapy with Tumor Irradiation, G. Sersa, S. Kranjc, and M. Cemazar Irreversible Electroporation in Medicine, B. Rubinsky Food and Biomaterials Processing Assisted by Electroporation, N. Lebovka and E. Vorobiev In Vivo Electroporation: An Important Injury Mechanism in Electrical Shock Trauma, I. Barakat, J. Gallaher, H. Chen, and R.C. Lee Index

Szczegóły: Advanced Electroporation Techniques in Biology and Medicine - Andrei G. Pakhomov, Damijan Miklavcic, Marko S. Markov

Tytuł: Advanced Electroporation Techniques in Biology and Medicine
Autor: Andrei G. Pakhomov, Damijan Miklavcic, Marko S. Markov
Producent: CRC Press Inc.
ISBN: 9781439819067
Rok produkcji: 2010
Ilość stron: 528
Oprawa: Twarda
Waga: 1.08 kg

Recenzje: Advanced Electroporation Techniques in Biology and Medicine - Andrei G. Pakhomov, Damijan Miklavcic, Marko S. Markov