Opis: Advances in Enzymology and Related Areas of Molecular Biology - Eric J. Toone

This book coversimportant advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. "With its discussion of current concepts of the biochemical basis of antibiotic resistance and its impact on modern medicine, this book will appeal to students, researchers, scientists, and clinicians interested in the areas of enzymology and mechanism of bacterial resistance." (Doody's, 26 August 2011)Contributors. Preface. Structure and Mechanism of RND-Type Multidrug Efflux Pumps ( Hiroshi Nikaido ). Efflux Pumps of Gram-Negative Bacteria: Genetic Responses to Stress and the Modulation of Their Activity by pH, Inhibitors, and Phenothiazines ( Leonard Amaral, Seamus Fanning, and Jean-Marie Pages ). Efflux Pumps of the Resistance-Nodulation-Division Family: A Perspective of Their Structure, Function, and Regulation in Gram-Negative Bacteria ( Mathew D. Routh, Yaramah Zalucki, Chih-Chia Su, Feng Long, Qijing Zhang, William M. Shafer, and Edward W. Yu ). The MFS Efflux Proteins of Gram-Positive and Gram-Negative Bacteria ( Massoud Saidijam, Kim E. Bettaney, Dong Leng, Pikyee Ma, Zhiqiang Xu, Jeffrey N. Keen, Nicholas G. Rutherford, Alison Ward, Peter J. F. Henderson, Gerda Szakonyi, Qinghu Ren, Ian T. Paulsen, Ingerid Nes, Jasmin K. Kroeger, and Anne-Brit Kolsto ). Efflux Pumps as an Important Mechanism for Quinolone Resistance ( Jordi Vila, Anna Fabrega, Ignasi Roca, Alvaro Hernandez, and Jose Luis Martinez ). Xenobiotic Efflux in Bacteria and Fungi: A Genomics Update ( Ravi D. Barabote, Jose Thekkiniath, Richard E. Strauss, Govindsamy Vediyappan, Joe A. Fralick, and Michael J. San Francisco ). A Survey of Oxidative Paracatalytic Reactions Catalyzed by Enzymes That Generate Carbanionic Intermediates: Implications for ROS Production, Cancer Etiology, and Neurodegenerative Diseases ( Victoria I. Bunik, John V. Schloss, John T. Pinto, Natalia Dudareva, and Arthur J. L. Cooper ). Author Index. Subject Index.

Szczegóły: Advances in Enzymology and Related Areas of Molecular Biology - Eric J. Toone

Tytuł: Advances in Enzymology and Related Areas of Molecular Biology
Autor: Eric J. Toone
Producent: John Wiley
ISBN: 9780470638354
Rok produkcji: 2011
Ilość stron: 300
Oprawa: Twarda
Waga: 0.76 kg

Recenzje: Advances in Enzymology and Related Areas of Molecular Biology - Eric J. Toone