Opis: The Chromosomal Imbalance Theory of Cancer - David Rasnick

Exploring the chromosomal imbalance (aneuploidy) theory of cancer, this volume describes how cancer is initiated and why progression takes years to decades. It clarifies why cancer cells often become drug resistant, provides objective, quantitative measures for detecting cancer and monitoring its progression, and suggests non-toxic strategies of cancer therapy and prevention. The book posits that the autocatalyzed progression of aneuploidy is carcinogenesis. The clarity and unifying simplicity of the theory of chromosomal imbalance has the potential to fundamentally alter the course of cancer research, prevention, diagnosis and treatment.Introducing Cancer Boveri's Theory of Cancer was Ahead of its Time: Aneuploidy theory "Got Lost". Genesis of "The Enemy Within"? Clonal cancer. Tumorigenic retroviruses. Dominate oncogenes. Tumor suppressor genes. Driver genes. Gene Mutation Theory of Cancer: "Carcinogens are mutagens". Retroviral oncogenes. Are "cellular oncogenes" like retroviral oncogenes? Updated gene mutation theory is popular but unconfirmed. The Chromosomal Imbalance Theory of Cancer: Heuristic explanation of how chromosomal imbalance (and not gene mutation) generates cancer phenotypes. Aneuploidy causes chromosomal instability-the hallmark of cancer. Cancer is a progressive somatic aneuploidy syndrome. Quantitative analysis of how aneuploidy generates new cellular phenotypes. Theory of Chromosomal Imbalance Solves Mysteries and Paradoxes: Carcinogenesis is dependent on aneuploidy and not mutation. Autocatalyzed progression of aneuploidy is carcinogenesis. Aneuploidy causes the Warburg effect by increasing ATP demand. Balanced mitotic forces and species-specific sequential chromatid separation may govern the rate of transformation. Cancer vaccine is very unlikely. "Cancers are a genuine type of species" New Perspectives for Cancer Prevention, Diagnosis and Therapy: International regulation of aneuploidy-inducing agents. Cancer detection. Cancer therapy. Conclusion

Szczegóły: The Chromosomal Imbalance Theory of Cancer - David Rasnick

Tytuł: The Chromosomal Imbalance Theory of Cancer
Autor: David Rasnick
Producent: Taylor
ISBN: 9781578087372
Rok produkcji: 2012
Ilość stron: 330
Oprawa: Twarda
Waga: 0.67 kg

Recenzje: The Chromosomal Imbalance Theory of Cancer - David Rasnick