Opis: Kidney in Plasma Cell Dyscrasias - G Herrera

In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias/myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of patients. Several chapters are devoted to various glomerulopathies associated with deposition of immunoglobulin light and heavy chains, including those associated with amyloidosis. The sequential events are pointed out, crucial steps and key molecules open to modulation or control are delineated, and therapeutic advances are highlighted. Although the emphasis is on the management of cases with renal involvement, a distinct focus on the diseases as a whole and their impact on patients' general health and prognosis has been maintained throughout the discussions. Using a translational approach to renal manifestations in patients with plasma cell dyscrasias/myelomas, this publication conveys a comprehensive state-of-the-art view of the subject. It is aimed at practicing renal pathologists, nephrologists, internists and hematologists, as well as at trainees and scientists working in these specialties.Introduction: The Kidney in Plasma Cell Dyscrasias: A Current View and a Look at the Future: Herrera, G.A.; A History of the Kidney in Plasma Cell Disorders: Steensma, D.P.; Kyle, R.A.; Pathologic Studies Useful for the Diagnosis and Monitoring of Plasma Cell Dyscrasias: Veillon, D.M.; Cotelingam, J.D.; Serum Free Light Chains in the Diagnosis and Monitoring of Patients with Plasma Cell Dyscrasias: Mayo, M.M.; Schaef Johns, G.; Mechanisms of Renal Damage in Plasma Cell Dyscrasias: An Overview: Merlini, G.; Pozzi, C.; Proximal Tubular Injury in Myeloma: Batuman, V.; Paraproteinemic Renal Diseases that Involve the Tubulo-Interstitium: Herrera, G.A.; Sanders, P.W.; The Mesangium as a Target for Glomerulopathic Light and Heavy Chains: Pathogenic Considerations in Light and Heavy Chain-Mediated Glomerular Damage: Keeling, J.; Herrera, G.A.; Immunoglobulin Light and Heavy Chain Amyloidosis AL/AH: Renal Pathology and Differential Diagnosis: Picken, M.M.; Diversity and Diversification of Light Chains in Myeloma: The Specter of Amyloidogenesis by Proxy: Gu, M.; Wilton, R.; Stevens, F.J.; High-Dose Therapy in Patients with Plasma Cell Dyscrasias and Renal Dysfunction: Pineda-Roman, M.; Tricot, G.; Current and Emerging Views and Treatments of Systemic Immunoglobulin Light-Chain (AL) Amyloidosis: Comenzo, R.L..

Szczegóły: Kidney in Plasma Cell Dyscrasias - G Herrera

Tytuł: Kidney in Plasma Cell Dyscrasias
Autor: G Herrera
Producent: Karger
ISBN: 9783805581783
Rok produkcji: 2006
Ilość stron: 216
Oprawa: Twarda
Waga: 0.6 kg

Recenzje: Kidney in Plasma Cell Dyscrasias - G Herrera