Opis: Karch's Pathology of Drug Abuse - Olaf Drummer, Steven Karch

Written in the same accessible manner as previous editions, the fifth edition of Karch's Pathology of Drug Abuse is an essential guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book focuses on the investigation of drug-related deaths, practical approaches to the detection of drug abuse, and discussions of medical complications associated with each of the abused drugs. The Fifth Edition Now Features: * Completely revised with hundreds of pages of wholly new coverage * Extensive discussion of new synthetic cannabinoids and cathinone derivatives * Expanded coverage of the functional and molecular pharmacology of cocaine and myocardial remodeling * Expanded discussion of deaths related to prescription medications * Detailed suggestions on the interpretation of postmortem drug measurements * Many new high resolution full-color photomicrographs * Additional, helpful new appendices on standard reference values Separate chapters are devoted to cocaine, naturally occurring stimulants, synthetic stimulants, hallucinogens, narcotics, anabolic steroids, disassociative anesthetics, solvent abuse, and marijuana. The book also offers detailed information on the origins, history, and production techniques used to make many of these drugs. Updated, revised, and newly illustrated, Karch's Pathology of Drug Abuse, Fifth Edition is a must-have reference for research and practice related to drug abuse. Steven B. Karch also discusses the book in a video on the CRC Press YouTube channel.Cocaine Prevalence of Abuse Epidemiology History Current Affairs Metabolism of Cocaine and Its Metabolites Fetal Metabolism Routes of Ingestion Problems of Cocaine Test Interpretation Cocaine Adulterants Cocaine Tissue Disposition and Postmortem Redistribution Electrophysiology of Sudden Death in Cocaine Abusers External Markers of Cocaine Abuse Skin Toxicity Cardiovascular System: General Overview Excited Delirium Syndrome Cocaine-Associated Pulmonary Disease Neurologic Disorders: Introduction Renal Disease Hematologic Abnormalities Hormonal Alterations Immune System Abnormalities Gastrointestinal Disorders Analytic and Forensic Toxicology Pregnancy Interactions When Is Cocaine the Cause of Death? References Natural Stimulants Absinthe Caffeine Ephedrine References Synthetic Stimulants Amphetamines Methylphenidate Captagon Other Stimulants New Synthetic Stimulants Cathinone Structural Analogs of Cathinone References Hallucinogens Introduction Production and Consumption Tryptamine Derivatives Hallucinogenic Amphetamines Phenylalkylamines Psilocybin alpha-Ethyltryptamine Lysergic Acid Diethylamide References Opiates and Opioids Worldwide Opium Consumption Epidemiology Classifying Narcotic and Nonnarcotic Agents History Cultivation and Manufacture Heroin Diluents and Adulterants Prices and Purity Morphine and Heroin Tissue Disposition Interpretation of Opiate Blood and Tissue Concentrations Synthetic Opioids: General Considerations Medical Consequences of Opiate Abuse Bioanalytic Considerations References Dissociative Anesthetics Introduction to Dissociative Anesthetics Phencyclidine Methoxetamine Ketamine Gamma-Hydroxybutyrate and Related Substances Pregabalin Salvia divinorum Dextromethorphan Propofol References Anabolic-Androgenic Steroids Prevalence and Epidemiology History Pharmacology Testosterone and Aging Patterns of Steroid Abuse Testosterone and Nandrolone Other Abused Steroids Legitimate Indications for Dispensing Anabolic-Androgenic Steroids Steroid-Related Disorders Selective Androgen Receptor Modulators Detecting Steroid Abuse in the Living Postmortem Analysis References Solvents Incidence and Epidemiology General Considerations: Availability and Types of Products Disposition: Absorption and Tissue Concentrations Pharmacology and Toxicology Clinical Syndromes Toxicology References Marijuana Botany Epidemiology Pharmacology Metabolism and Disposition Detection Times Cardiovascular Effects Pulmonary Complications Synthetic Cannabinoids Selective THC Agents Postmortem Considerations Toxicology References Appendix A: Conversion Formulas Appendix B: Blood Ethanol Concentrations Appendix C: Volume of Distribution Calculations Appendix D: Methods for Determining Normal Heart Weight Appendix E: Normal Organ Weights Appendix F: Collecting and Documenting Pills from the Scene of a Death

Szczegóły: Karch's Pathology of Drug Abuse - Olaf Drummer, Steven Karch

Tytuł: Karch's Pathology of Drug Abuse
Autor: Olaf Drummer, Steven Karch
Producent: CRC Press Inc.
ISBN: 9781439861462
Rok produkcji: 2014
Ilość stron: 906
Oprawa: Twarda
Waga: 2.06 kg

Recenzje: Karch's Pathology of Drug Abuse - Olaf Drummer, Steven Karch