Opis: Discrete Event Simulation for Health Technology Assessment - Jack Ishak, Jonathan Karnon, James Stahl

Discover How to Apply DES to Problems Encountered in HTA Discrete event simulation (DES) has traditionally been used in the engineering and operations research fields. The use of DES to inform decisions about health technologies is still in its infancy. Written by specialists at the forefront of this area, Discrete Event Simulation for Health Technology Assessment is the first book to make all the central concepts of DES relevant for health technology assessment (HTA). Accessible to beginners, the book requires no prerequisites and describes the concepts with as little jargon as possible. The book first covers the essential concepts and their implementation. It next provides a fully worked out example using both a widely available spreadsheet program (Microsoft Excel) and a popular specialized simulation package (Arena). It then presents approaches to analyze the simulations, including the treatment of uncertainty; tackles the development of the required equations; explains the techniques to verify that the models are as efficient as possible; and explores the indispensable topic of validation. The book also covers a variety of non-essential yet handy topics, such as the animation of a simulation and extensions of DES, and incorporates a real case study involving screening strategies for breast cancer surveillance. This book guides you in leveraging DES in your assessments of health technologies. After reading the chapters in sequence, you will be able to construct a realistic model designed to help in the assessment of a new health technology.Introduction The HTA Context What Is Discrete Event Simulation? How Does DES Compare to Other Techniques Commonly Used in HTA? When Is Discrete Event Simulation Useful? Acceptance of Discrete Event Simulation Central Concepts Events Event Occurrence Entities Attributes Time Resources and Queues Global Information Distributions Using Influence Diagrams Implementation Control Logic Using Distributions Event Handling Specifying Events Creating the Population Assigning Attributes Handling Time Applying Intervention Effects Recording Information Reflecting Resource Use A Simple Example Design Obtaining the Inputs Structuring the Model Obtaining Results Analyses Base Case Exploring Sensitivity to Input Values Formulating the Required Equations Requirements for the Equations Selecting Data Sources Taxonomy of Equation Types Commonly Used in DES Selection of Predictors Validation of the Final Equation Combining Inputs and Equations from Different Sources Efficiency and Variance Reduction Reducing Unwanted Variance Other Efficiency Improvements Settings Affecting Model Execution Validation Face Validity Verification External Validation Special Topics Documentation Animation Software Agent-Based Models Hybrid Models Case Study: Breast Cancer Surveillance Background Why DES? Design Data Sources Implementation Analyses Results Comments

Szczegóły: Discrete Event Simulation for Health Technology Assessment - Jack Ishak, Jonathan Karnon, James Stahl

Tytuł: Discrete Event Simulation for Health Technology Assessment
Autor: Jack Ishak, Jonathan Karnon, James Stahl
Producent: Apple
ISBN: 9781482218244
Rok produkcji: 2015
Ilość stron: 374
Oprawa: Twarda
Waga: 0.66 kg

Recenzje: Discrete Event Simulation for Health Technology Assessment - Jack Ishak, Jonathan Karnon, James Stahl