Opis: Host - Pathogen Interaction - Anja Schuffler, Eckhard Thines, Gottfried Unden

In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.Preface VII Cover Legend IX List of Contributors XI Part One Adaptation of Microbial Metabolism in Host/Pathogen Interaction 1 1 Metabolic Adaptation of Human Pathogenic Yersiniae 3 Ann Kathrin Heroven and Petra Dersch* 2 Crosstalk between Metabolism and Virulence of Legionella pneumophila 19 Klaus Heuner andWolfgang Eisenreich* 3 Metabolism of Intracellular Salmonella enterica 37 Peter Holtk otter and Michael Hensel* 4 The Human Microbiome in Health and Disease 57 Cian Hill, R. Paul Ross, Catherine Stanton, and Paul W. O Toole* 5 Mechanisms of Dysbiosis in the Inflamed Gut 77 Sebastian E. Winter* 6 Strategies for Nutrient Acquisition by Magnaporthe oryzae during the Infection of Rice 93 Andrew J. Foster, George R. Littlejohn, Darren M. Soanes, and Nicholas J. Talbot* Part Two New Inhibitors and Targets of Infectious Diseases 109 7 Outer Membrane Proteins as Potential Anti-infective Drug Targets in Mannheimia haemolytica 111 Robert L. Davies* 8 Identification of Anti-infective Compounds Using Amoebae 139 Christopher F. Harrison and Hubert Hilbi* 9 Stress Biology in Fungi and Omic Approaches as Suitable Tools for Analyzing Plant Microbe Interactions 153 Stefan Jacob* and Alexander Yemelin 10 Targeting Plasmids: NewWays to Plasmid Curing 179 Anja Sch uffler* and Corinna K ubler 11 Regulation of SecondaryMetabolism in the Gray Mold Fungus Botrytis cinerea 201 Muriel Viaud*, Julia Schumacher, Antoine Porquier, and Adeline Simon Index 217

Szczegóły: Host - Pathogen Interaction - Anja Schuffler, Eckhard Thines, Gottfried Unden

Tytuł: Host - Pathogen Interaction
Autor: Anja Schuffler, Eckhard Thines, Gottfried Unden
Wydawnictwo: VCH
ISBN: 9783527337453
Rok wydania: 2016
Ilość stron: 240
Oprawa: Twarda
Waga: 0.67 kg

Recenzje: Host - Pathogen Interaction - Anja Schuffler, Eckhard Thines, Gottfried Unden