Opis: Fetal and Neonatal Physiology - William Benitz, David Rowitch, Steven Abman

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this 2-volume resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner.Section I - Genetics and Embryology * Basic Genetic Principles * Prenatal Diagnosis * Basic Embryology * Regulation of Embryogenesis * The Extracellular Matrix in Development * Stem Cell Biology * Apoptotic Cell Death * Angiogenesis * Epigenetics Section II - Placenta and Intrauterine Environment * Placental Development * Regulation of the Placental Circulation * Mechanisms of Transfer Across the Human Placenta * Endocrine and Paracrine Function of the Human Placenta * Fetal and Maternal Responses to Intrauterine Infection * Fetal Origins of Adult Disease: A Classic Hypothesis with New Relevance * Physiologic Effects of Multiple Pregnancy on Mother and Fetus * Placental function in intrauterine growth restriction Section III - Developmental Pharmacology and Pharmacokinetics * Basic Pharmacologic Principles * Principles of Pharmacokinetics * Physicochemical and Structural Properties Regulating Placental Drug Transfer * Pharmacogenetics * Drug Distribution in Fetal Life * Drug Transfer During Breastfeeding Section IV - Intrauterine and Postnatal Growth * Circulatory and Metabolic Changes Accompanying Fetal Growth Restriction * Endocrine Factors Affecting Neonatal Growth * Human Milk Composition and Function in the Infant * Physiology of Lactation Section V - Perinatal Iron, Mineral, and Vitamin Metabolism * Fetal and Neonatal Iron Metabolism * Neonatal Calcium, Phosphorus, and Magnesium Homeostasis * Zinc in the Fetus and Neonate * Vitamin A Metabolism in the Fetus and Neonate * Vitamin E Metabolism in the Fetus and Newborn Infant * Vitamin K Metabolism in the Fetus and Neonate Section VI - Lipid Metabolism * Maternal-Fetal Transfer of Lipid Metabolites * Brown Adipose Tissue: Development and Function * Lipids as an Energy Source for the Premature and Full-Term Neonate * Ketone Body Production and Metabolism in the Fetus and Neonate * Long-Chain Fatty Acids in the Developing Retina and Brain Section VII - Carbohydrate Metabolism * Metabolism of Glucose and Methods of Investigation in the Fetus and Newborn * Carbohydrate Metabolism During Pregnancy * Oxygen Consumption and General Carbohydrate Metabolism of the Fetus * Role of Glucoregulatory Hormones in Hepatic Glucose Metabolism During the Perinatal Period * Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development Section VIII - Protein Metabolism * General Concepts of Protein Metabolism * Fetal Requirements and Placental Transfer of Nitrogenous Compounds Section IX - Thermoregulation * Temperature Control in Newborn Infants * Responses of the Fetus and Neonate to Hypothermia Section X - Skin * Structure and Development of Skin and Cutaneous Appendages * Physiologic Development of the Skin Section XI - Fetal and Neonatal Cardiovascular Physiology * Cardiovascular Development * Developmental Electrophysiology in the Fetus and Neonate * Developmental Biology of the Pulmonary Vasculature * Development of the Gastrointestinal Circulation in the Fetus and Newborn * Physiology of Congenital Heart Disease in the Neonate * Neural Regulation of Blood Pressure During Fetal and Newborn Life * Developmental Effects on Fetal Circulation * Mechanisms Regulating Closure of the Ductus Arteriosus * Umbilical Circulation * Fetal and Placental Circulation During Labor * Physiology of Resuscitation Section XII - The Lung * Normal and Abnormal Structural Development of the Lung * Regulation of Alveolarization * Physiologic Mechanisms of Normal and Altered Lung Growth Before and After Birth * Molecular Mechanisms of Lung Development and Lung Branching Morphogenesis * Regulation of Liquid Secretion and Absorption by the Fetal and Neonatal Lung * Upper Airway Structure: Function, Regulation, and Development * Regulation of Lower Airway Function * Functional Development of Respiratory Muscles * Mechanics of Breathing * Pulmonary Gas Exchange in the Developing Lung * Oxygen Transport and Delivery * Control of Breathing in Fetal Life and Onset and Control of Breathing in the Neonate * Basic Mechanisms of Oxygen Sensing and Response to Hypoxia * Evaluation of Pulmonary Function in the Neonate * Mechanisms of Neonatal Lung Injury * Impaired Lung Growth After Injury in Premature Lung * Antenatal Factors That Influence Postnatal Lung Development and Injury * Regulation of Pulmonary Circulation Section XIII - Surfactant * Historical Perspective * Composition of Pulmonary Surfactant Lipids and Proteins * Structure And Development of Alveolar Epithelial Cells * Regulation of Surfactant-Associated Phospholipid Synthesis and Secretion * Hormonal Therapy for Prevention of Respiratory Distress Syndrome * Surfactant Treatment * Genetics and Physiology of Surfactant Protein Deficiencies Section XIV - Physiology of Gastrointestinal Tract in the Fetus and Neonate * Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development * Organogenesis of the Gastrointestinal Tract * Development of the Enteric Nervous System * Development of Gastric Secretory Function * Development of Gastrointestinal Motility * Development of the Exocrine Pancreas * Digestive-Absorption Functions in Fetuses, Infants, and Children * Development of the Intestinal Microbiome Section XV - Liver and Bilirubin Metabolism * Organogenesis and Histologic Development of the Liver * Bile Acid Metabolism During Development * Neonatal Bilirubin Metabolism * Hereditary Contribution to Neonatal Hyperbilirubinemia * Mechanisms of Action of Phototherapy for Neonatal Hyperbilirubinemia Section XVI - The Kidney * Embryogenesis and Anatomic Development of the Kidney * Functional Development of the Kidney in Utero * Development and Regulation of Renal Blood flow in the Neonate * Development of the Renin-Angiotensin System * Postnatal Development of Glomerular Filtration Rate in Neonates * Renal Transport of Sodium During Early Development * Potassium Homeostasis in the Fetus and Neonate * Role of the Kidney in Calcium and Phosphorus Homeostasis * Transport of Amino Acids in the Fetus and Neonate * Developmental Aspects of Organic Acid Transport * Concentration and Dilution of the Urine * Development of Acidification Mechanisms in the Fetus and Neonate * Response to Nephron Loss in Early Development Section XVII - Fluid and Electrolyte Metabolism * Fluid Distribution in the Fetus and Neonate * Regulation of Acid-Base Balance in the Fetus and Neonate Section XVIII - Developmental Hematopoiesis * Developmental Biology of Stem Cells: From the Embryo to the Adult * Developmental Granulocytopoiesis * Developmental Erythropoiesis * Developmental Megakaryocytopoiesis Section XIX - Hemostasis * Developmental Hemostasis * Platelet-Vessel Wall Interactions Section XX - Developmental Immunobiology * Host Defense Mechanisms Against Bacteria * Host-Fungi Interactions Relevant to the Newborn Infant * Host Defense Mechanisms Against Viruses * T-Cell Development * B-Cell Development * Mononuclear Phagocyte System * Normal and Abnormal Neutrophil Physiology in the Newborn * The Complement System of the Fetus and Newborn * Cytokines and Inflammatory Response in the Fetus and Neonate * Immunology of Human Milk and Host Immunity * Neonatal Pulmonary Host Defense Section XXI - Neurology * Development of the Nervous System * Development of the Blood-Brain Barrier * Trophic Factor and Nutritional and Hormonal Regulation of Brain Development * Intraventricular Hemorrhage in the Neonate * Cerebellar Development - an Impact of Preterm Birth and Co-Morbidities * Electroencephalography in the Premature and Full-Term Infant * Developmental Aspects of Pain Section XXII - Special Sensory Systems in the Fetus and Neonate * Early Development of the Human Auditory System * Development of Taste and Smell in the Neonate Section XXIII - Orthopedics * The Growth Plate: Embryologic Origin, Structure, and Function * Ontogenesis of Striated Muscle Section XXIV - Endocrine Function * Hypothalamus: Neuroendometabolic Center * Growth Factor Regulation of Fetal Growth * Growth Hormone in the Fetus and Newborn * Luteinizing Hormone and Follicle-Stimulating Hormone Secretion in the Fetus and Newborn * Development of the Corticotropin-Releasing Hormone-Corticotropin System in the Mammalian Fetus * Fetal and Neonatal Adrenocortical Physiology * Fetal and Neonatal Thyroid Physiology Section XXV - Ovary and Testis * Genetics of Sex Determination and Differentiation * Differentiation of the Ovary * Testicular Development and Descent Section XXVI - Pathophysiology of Neonatal Diseases * Pathophysiology of Neonatal sepsis * Pathophysiology of Hypoglycemia in the Neonate * Pathophysiology of Cardiomyopathies * Pathophysiology of Persistent pulmonary hypertension of the newborn * Pathophysiology of Shock in the Fetus and Neonate * Pathophysiology of Apnea of Prematurity * Pathophysiology of Respiratory Distress Syndrome * Pathophysiology of Meconium Aspiration Syndrome * Pathophysiology of Bronchopulmonary Dysplasia * Pathophysiology of Ventilator Dependent Infants * Pathophysiology of Gastroesophageal Reflux * Pathophysiology of Neonatal Necrotizing Enterocolitis * Pathophysiology of Kernicterus * Pathophysiology of neonatal acute kidney injury * Pathophysiology of Edema * Pathophysiology of Retinopathy of Prematurity * Pathophysiology of Hypoxic-ischemic Brain Injury * Pathophysiology of Neonatal White Matter Injury * Pathophysiology of Meningitis * Pathophysiology of Neural Tube Defects * Pathophysiology of Preeclampsia * Pathophysiology of Preterm Birth * Pathophysiology of Chorioamnionitis

Szczegóły: Fetal and Neonatal Physiology - William Benitz, David Rowitch, Steven Abman

Tytuł: Fetal and Neonatal Physiology
Autor: William Benitz, David Rowitch, Steven Abman
Wydawnictwo: Elsevier Science Publishers
ISBN: 9780323352147
Rok wydania: 2016
Ilość stron: 1928

Recenzje: Fetal and Neonatal Physiology - William Benitz, David Rowitch, Steven Abman