Opis: Computational Hydrodynamics of Capsules and Biological Cells - C Pozrikidis

Spanning biological, mathematical, computational, and engineering sciences, Computational Biofluiddynamics addresses a diverse family of problems involving fluid flow inside and around living organisms, organs, tissue, biological cells, and other biological materials. "Computational Hydrodynamics of Capsules and Biological Cells" provides a comprehensive, rigorous, and current introduction to the fundamental concepts, mathematical formulation, alternative approaches, and predictions of this evolving field. In the first several chapters on boundary-element, boundary-integral, and immersed-boundary methods, the book covers the flow-induced deformation of idealized two-dimensional red blood cells in Stokes flow, capsules with spherical unstressed shapes based on direct and variational formulations, and cellular flow in domains with complex geometry. It also presents simulations of microscopic hemodynamics and hemorheology as well as results on the deformation of capsules and cells in dilute and dense suspensions. The book then describes a discrete membrane model where a surface network of viscoelastic links emulates the spectrin network of the cytoskeleton, before presenting a novel two-dimensional model of red and white blood cell motion. The final chapter discusses the numerical simulation of platelet motion near a wall representing injured tissue. This volume provides a roadmap to the current state of the art in computational cellular mechanics and biofluiddynamics. It also indicates areas for further work on mathematical formulation and numerical implementation and identifies physiological problems that need to be addressed in future research. This book gives a quite extensive overview of different possible formulations for the motion of rigid or deforming particles and for the solution of flow-induced deformations. A wide range of numerical and methodological approaches are illustrated ... The presence of many numerical examples allows one to appreciate the capabilities of the approaches proposed and provides useful reference material. ... this book is a highly valuable reference for any graduate student or researcher interested in cellular mechanics, bio-fluid dynamics, bio-rheology or, in general, applications involving the transport of micro-capsules or cells by a fluid. It is accompanied by an Internet site where some additional material, including MATLAB code, may be found. -Luca Formaggia, Mathematical Reviews, Issue 2012aFlow-Induced Deformation of Two-Dimensional Biconcave Capsules, C. Pozrikidis Introduction Mathematical framework Numerical method Cell shapes and dimensionless numbers Capsule deformation in infinite shear flow Capsule motion near a wall Discussion Flow-Induced Deformation of Artificial Capsules, D. Barthes-Biesel, J. Walter, and A.-V. Salsac Introduction Membrane mechanics Capsule dynamics in flow B-spline projection Coupling finite elements and boundary integrals Capsule deformation in linear shear flow Discussion A High-Resolution Fast Boundary-Integral Method for Multiple Interacting Blood Cells, Jonathan B. Freund and Hong Zhao Introduction Mathematical framework Fast summation in boundary-integral computations Membrane mechanics Numerical fidelity Simulations Summary and outlook Simulating Microscopic Hemodynamics and Hemorheology with the Immersed-Boundary Lattice-Boltzmann Method, J. Zhang, P. C. Johnson, and A.S. Popel Introduction The lattice-Boltzmann method The immersed-boundary method Fluid property updating Models of RBC mechanics and aggregation Single cells and groups of cells Cell suspension flow in microvessels Summary and discussion Front-Tracking Methods for Capsules, Vesicles, and Blood Cells, Prosenjit Bagchi Introduction Numerical method Capsule deformation in simple shear flow Capsule interception Capsule motion near a wall Suspension flow in a channel Rolling on an adhesive substrate Summary Dissipative Particle Dynamics Modeling of Red Blood Cells, D.A. Fedosov, B. Caswell, and G.E. Karniadakis Introduction Mathematical framework Membrane mechanical properties Membrane-solvent interfacial conditions Numerical and physical scaling Membrane mechanics Membrane rheology from twisting torque cytometry Cell deformation in shear flow Tube flow Summary Simulation of Red Blood Cell Motion in Microvessels and Bifurcations, T.W. Secomb Introduction Axisymmetric models for single-file RBC motion Two-dimensional models for RBC motion Tank-treading in simple shear flow Channel flow Motion through diverging bifurcations Motion of multiple cells Discussion Multiscale Modeling of Transport and Receptor-Mediated Adhesion of Platelets in the Bloodstream, N.A. Mody and M.R. King Introduction Mathematical framework Motion of an oblate spheroid near a wall in shear flow Brownian motion Shape and wall effects on hydrodynamic collision Transient aggregation of two platelets near a wall Conclusions and future directions Index

Szczegóły: Computational Hydrodynamics of Capsules and Biological Cells - C Pozrikidis

Tytuł: Computational Hydrodynamics of Capsules and Biological Cells
Autor: C Pozrikidis
Producent: CRC Press Inc.
ISBN: 9781439820056
Rok produkcji: 2010
Ilość stron: 327
Oprawa: Twarda
Waga: 0.61 kg

Recenzje: Computational Hydrodynamics of Capsules and Biological Cells - C Pozrikidis