Opis: Biotechnology of Bioactive Compounds

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine.

Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds.

Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

List of contributors ix

Foreword xvii

Preface xix

Section I: Bioactive compounds from diverse plant microbialand marine sources

1 Bioactive compounds from vegetable and fruit by-products3 B. De Ancos C. Colina-Coca D. Gonzalez-Pena and C.Sanchez-Moreno

2 Bioactive compounds in fresh-cut fruits: Occurrence and impactof processing and cold storage 37 Maria Elida Pirovani Andrea Marcela Piagentini and FrancoVan de Velde

3 Pressurized hot water extraction of polyphenols from plantmaterial 63 Jose Rodrigo Vergara-Salinas Jose Cuevas-Valenzuelaand Jose R. Perez-Correa

4 Bioactive compounds in cereals: Technological and nutritionalproperties 103 Bart3omiej Makowski Justyna Rosicka-Kaczmarek and EwaNebesny

5 Antimicrobials from medicinal plants: Research initiativeschallenges and the future prospects 123 Anita Pandey and Vasudha Agnihotri

6 Coccoloba uvifera as a source of components with antioxidantactivity 151 Maira Segura Campos Jorge Ruiz Ruiz Luis Chel Guerrero and DavidBetancur Ancona

7 Bioactive compounds and medical significance of someendangered medicinal plants from the Western Ghats region of India163 Manoharan Melvin Joe Abitha Benson Muniappan Ayyanar and TongminSa

8 Fungal bioactive compounds: An overview 195 Gerardo Diaz-Godinez

9 Arbuscular mycorrhizal fungi: Association and production ofbioactive compounds in plants 225 Marcela C. Pagano and Partha P. Dhar

10 Extremophiles as source of novel bioactive compounds withindustrial potential 245 Mohamed Neifar Sameh Maktouf Raoudha Ellouze Ghorbel AtefJaouani and Ameur Cherif

11 New trends in microbial production of natural complexbioactive isoprenoids 269 Rama Raju Baadhe Ravichandra Potumarthi Naveen Kumar Mekala andVijai K. Gupta

12 Production of c-phycocyanin and its potential applications283 Mohammed Kuddus Poonam Singh George Thomas and Athar Ali

Section II: Chemistry biotechnology and industrialrelevance

13 Glycosides: From biosynthesis to biological activity towardtherapeutic application 303 Maria Henriques L. Ribeiro

14 Trehalose mimics as bioactive compounds 345 Davide Bini Antonella Sgambato Luca Gabrielli Laura Russo andLaura Cipolla

15 Virtual screening and prediction of the molecular mechanismof bioactive compounds in silico 371 Bashir A. Akhoon Krishna P. Singh Madhumita Karmakar Suchi SmitaRakesh Pandey and Shailendra K. Gupta

16 Steroids in natural matrices: Chemical features and bioactiveproperties 395 Joao C.M. Barreira and Isabel C.F.R. Ferreira

17 Bioactive compounds obtained through biotechnology 433 Gustavo Molina Franciele M. Pelissari Marina G. Pessoa andGlaucia M. Pastore

18 Metabolic engineering of bioactive compounds in berries463 Ivayla Dincheva Ilian Badjakov and Violeta Kondakova

19 Food-derived multifunctional bioactive proteins and peptides:Sources and production 483 Dominic Agyei Ravichandra Potumarthi and Michael K.Danquah

20 Food-derived multifunctional bioactive proteins and peptides:Applications and recent advances 507 Dominic Agyei Ravichandra Potumarthi and Michael K.Danquah

Section III: Biochemistry and nutraceutical or health-relatedapplications

21 An overview of the molecular and cellular interactions ofsome bioactive compounds 527 Amro Abd Al Fattah Amara

22 Bioactive compounds as growth factors and 3D matrix materialsin stem cell research 555 Naveen Kumar Mekala Rama Raju Baadhe and RavichandraPotumarthi

23 Phytosterols: Biological effects and mechanisms ofhypocholesterolemic action 565 Rafaela da Silva Marineli Cibele Priscila Busch Furlan Anne yCastro Marques Juliano Bicas Glaucia Maria Pastore andMario Roberto Marostica Jr.

24 Overview of the role of food bioactive compounds ascomplementary therapy for celiac disease 583 Antonio Cilla Laia Alemany Juan Antonio Gimenez andJose Moises Laparra

25 Bioactive lipid components from ruminant milk and meat: Thenew face of human health 599 Malgorzata Szumacher-Strabel Mohamed El-Sherbiny Adam CieslakJoanna Szczechowiak and Hanna Winiarska

26 The milk fat globule membrane: A potential source ofhealth-promoting glycans 631 Sarah A. Ross Jonathan A. Lane Michelle Kilcoyne Lokesh Joshiand Rita M. Hickey

27 Seaweed and milk derived bioactive peptides and smallmolecules in functional foods and cosmeceuticals 669 Maria Hayes Melani Garcia-Garcia CiaranFitzgerald and Tomas Lafarga

Index 693

Szczegóły: Biotechnology of Bioactive Compounds

Tytuł: Biotechnology of Bioactive Compounds
Producent: Blackwell Science
ISBN: 9781118733493
Rok produkcji: 2015
Ilość stron: 736
Oprawa: Twarda
Waga: 1.23 kg

Recenzje: Biotechnology of Bioactive Compounds