Opis: Telomeres - De Lange

An up-to-date survey of the current exciting state of telomere biology. Telomeres - specialized structures found at the ends of chromosomes - are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging. ...a 'must have' for all telomere aficionados. The book will also be very valuable to undergraduates seeking advanced knowledge and to graduate students and other newcomers to the telomere field... Genetical Research The second edition of Telomeres is an outstanding summary of what has become an area of biology with substantial range and depth. It has proven a treasure trove for researchers ranging from enzymologists and structural biologists to developmental and cancer biologists to gerontologists. This book is a compact guide to the exciting findings pertinent to these diverse fields. Written and edited by major leaders of this field, this volume is well referenced and will be of great use to educators of college, graduate, and medical students. The Quarterly Review of Biology1. A History of Telomere Biology 2. The Telomerase Ribonucleoprotein Particle 3. Telomerase Biochemistry and Biogenesis 4. Telomerase and Human Cancer 5. Modeling Cancer and Aging in the Telomerase-deficient Mouse 6. Telomerase Deficiency and Human Disease 7. Telomerase-independent Maintenance of Mammalian Telomeres 8. Telomerase-independent Telomere Maintenance in Yeast 9. Meiotic Telomeres 10. Telomere Position Effect: Silencing Near the End 11. The Structural Biology of Telomeres 12. Budding Yeast Telomeres 13. Mammalian Telomeres 14. Drosophila Telomeres 15. Ciliate Telomeres 16. Fission Yeast Telomeres 17. Plant Telomeres Appendix: A Personal Account of The Discovery of Telomerase Index

Szczegóły: Telomeres - De Lange

Tytuł: Telomeres
Autor: De Lange
Producent: Cold Spring Harbor Laboratory Press
ISBN: 9780879697341
Rok produkcji: 2005
Ilość stron: 576
Oprawa: Twarda
Waga: 1.1 kg

Recenzje: Telomeres - De Lange